Welcome to our Lab
Advancing Pathogen Research: Genomic Insights and Innovative Solutions for Combating Antibiotic Resistance
Our research focuses on the isolation, characterization, and identification of human pathogenic bacteria from diverse clinical and environmental samples. By employing advanced techniques such as 16s rRNA sequencing, whole genome sequencing (WGS), we investigate the genetic makeup of these bacteria, with a special emphasis on identifying antibiotic resistance genes. Additionally, we perform in silico molecular docking, dynamics simulations, and density functional theory (DFT) studies to discover potential inhibitors targeting these resistance mechanisms. Our work aims to combat the rising threat of antimicrobial resistance by uncovering novel therapeutic strategies and enhancing our understanding of bacterial pathogenesis.
Innovative Compound Synthesis and Natural Product Discovery for Therapeutic Applications
In addition to our pathogen research, we specialize in medicinal chemistry, where we synthesize novel compounds and characterize them using advanced techniques like UV, GC-MS, FTIR, NMR, XRD, SEM, and TGA. These compounds are evaluated for their biological activities, including antimicrobial, anticancer, antidiabetic, cytotoxicity, and antioxidant properties. Our work also extends to the investigation of plant extracts, utilizing advanced analytical methods to discover potential therapeutic compounds from nature, driving innovation in drug development and natural product research.
Significance of our research in Scientific Research and Human Health
Our research plays a crucial role in advancing both scientific knowledge and human health. The identification of antibiotic-resistant bacteria and potential inhibitors helps address the global threat of antimicrobial resistance, a growing public health crisis. By investigating the mechanisms behind bacterial resistance and finding novel therapeutic targets, we contribute to the development of new treatments that can overcome drug-resistant infections.
In the field of medicinal chemistry, our synthesis and characterization of novel compounds, along with the exploration of bioactive molecules from plant extracts, are vital for discovering new drugs. These efforts hold immense potential for treating a wide range of diseases, including cancer, diabetes, and infectious diseases. The evaluation of biological activities like antimicrobial, anticancer, and antioxidant properties helps us find safer, more effective therapies, improving patient outcomes and contributing to global healthcare solutions.